##  [Wolff's Law](/wolffs-law) 

  ##  [Wolff's Law](https://health.quantumdictionary.io/wolffs-law-0) 

  

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**Health & Life Sciences Dictionary**

 







 

 

 

 



 

 

 

 

Definition

Biological principle stating that bone tissue remodels its micro‑ and macro‑architecture over time in response to the magnitude, frequency and direction of mechanical loads applied to it; remodeling alters bone mass distribution and trabecular orientation through cellular processes (mechanosensing and the coupled activities of osteocytes, osteoblasts and osteoclasts) and is modulated by biological