##  [Sequence Conservation](/sequence-conservation) 

  ##  [Sequence Conservation](https://natural.quantumdictionary.io/sequence-conservation-0) 

  

 [![Natural & Formal Sciences Dictionary](/sites/default/files/styles/large/public/2026-01/Natural%20%26%20Formal%20Sciences.png.webp?itok=2kCDRVQv)](/topic-specific-dictionaries/natural-formal-sciences)



**Natural & Formal Sciences Dictionary**

 







 

 

 

 



 

 

 

 

Definition

Retention of nucleotide or amino-acid sequence similarity across species, paralogs, or time, indicative of functional, structural, or selective constraint acting on the sequence.