 ##  [Loss of Intracellular Compartmentalization](/loss-intracellular-compartmentalization) 

  ##  [Loss of Intracellular Compartmentalization](https://natural.quantumdictionary.io/loss-intracellular-compartmentalization-0) 

  
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**Natural &amp; Formal Sciences Dictionary**

 
Definition

Failure to maintain distinct organelle or subcellular compartment boundaries leading to mixing of contents and loss of localized biochemical environments; in this dictionary it denotes pathological breakdown of membrane-based separation within the cell.