 ##  [Armitage–Doll Multistage Model of Carcinogenesis](/index.php/armitage-doll-multistage-model-carcinogenesis) 

  ##  [Armitage–Doll Multistage Model of Carcinogenesis](https://health.quantumdictionary.io/armitage-doll-multistage-model-carcinogenesis-0) 

  

 [![Health & Life Sciences Dictionary](/sites/default/files/styles/large/public/2026-01/Health%20%26%20Life%20Sciences.png.webp?itok=yyyaiQOY)](/index.php/topic-specific-dictionaries/health-life-sciences)



**Health &amp; Life Sciences Dictionary**

 







 

 

 

 



 

 

 

 

Definition

A mathematical framework proposing that cancer arises through a sequence of multiple, rate‑limiting stages (biological events or transitions) whose accumulation over time produces characteristic age‑incidence patterns; in its simplest form, the model predicts a power‑law relationship between age and incidence tied to the number of rate‑limiting stages.