##  [Allostatic Load Model](/index.php/allostatic-load-model) 

  ##  [Allostatic Load Model](https://health.quantumdictionary.io/allostatic-load-model-0) 

  

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**Health & Life Sciences Dictionary**

 







 

 

 

 



 

 

 

 

Definition

A physiological model that explains how repeated or chronic activation, dysregulation, or inadequate termination of adaptive stress-response systems (neuroendocrine, autonomic, immune, metabolic) accumulates as multisystem ‘wear and tear’—measurable by a constellation of biomarkers—and thereby increases the probability of morbidity and functional decline over time.