##  [Affinity Maturation](/affinity-maturation) 

  ##  [Affinity Maturation](https://health.quantumdictionary.io/affinity-maturation-0) 

  

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**Health & Life Sciences Dictionary**

 







 

 

 

 



 

 

 

 

Definition

Germinal center process in which B cell clones acquire, through iterative cycles of somatic hypermutation and selection, an increased average binding affinity of their immunoglobulin receptors for antigen, resulting in production of higher‑affinity antibodies and durable memory.